Nutrigenomics is the study of the interaction(s) between a person’s nutrition and their unique genes.
Your body holds trillions of cells, each with the same instructions personalized to you through your unique DNA. The DNA in each cell is arranged into pairs of chromosomes. Your 23 pairs of chromosomes are then arranged into short segments of DNA-- genes. These genes proceed to dictate what processes occur within the cells, eventually building up every part of your body and helping it continue to function properly.
The Human Genome Project completed in 2003, providing scientists with a blueprint of the approximately 20,500 genes that make up human beings. Think of it as a map of how humans are built. It shows us what's deep in our cells that make us unique: different heights, different eye colors, different risks for diseases, etc.
Genes are important to the framework and function of the human body. They hold a unique recipe for every protein and direct biological pathways in the body. One gene may make one type of protein, another gene will make another type of protein. It is proteins that make us who we are (physically). Proteins are fundamental to life and our health. They lie at the heart of how our bodies function. They direct everything from how we are built and move, to things we don’t think about like breathing and digesting our food. Some proteins become muscle while some become hormones, enzymes, cell receptors, or bone, for example.
Important new information has become available, showing how strong the link is between nutrition and other vital organs, especially the gut-brain connection. The food we eat is not just calories. It is information, that triggers other processes. 90% of serotonin comes from our gut!
The food we eat is not just for us- it's for our vibrant microbiome of bacteria living in our intestines in a symbiotic relationship. We supply the bacteria food and they provide other functions- they they help digest the food we eat, help keep our gut clear of nasty bacteria, and they release hormones. What else do they do? We are just learning.
The sunlight you feel on your skin is not just warm. It is a trigger for mitochondria. The sunlight is a trigger for melatonin and serotonin release.
Our environment, emotional stress, and epigenetics strongly influence our inherent genetic predisposition
This, combined with our unique DNA, helps fuel vital metabolic processes:
Your DNA and polymorphisms (SNPs)
Free radicals, oxidative stress
Hormone release and balance
Vitamins (like vitamin D)
Essential elements (like magnesium)
Omega 3, Omega 6
Apo E (Apolipoprotein E 4)
Fox03 gene (longevity gene)
Coronary Artery Disease
Brain disorders including
Great explanation of DNA, and basis for nutrigenomics. Essential viewing for anyone thinking of nutritional genetic testing. It's complicated, but this video helps simplify it
Your gut as a hormonal organ. Astonishing. A must hear
Goal of restoring the relationship between microbe and man
Half of us are not getting enough magnesium. Explains why eating our greens is so important!
Should you be eating barbecue meats? Your DNA will tell you
Do you have Vitamin D deficiency? Everyone should be tested Adequate levels 30-60 ng/ ml
Do you have a CYP2R1 mutation that could increase your risk for cancer?
Maternal antibodies against fetal brain cells 4 x more likely with autism. Would taking vitamin D help reduce autism?
Stress intolerance and nutrigenomics, and epigenetics
Introduction to Nutritional Genomics
Polymorphisms and SNPs
Dr. Patrick is a very good educator!
For physicians MTHR and other essentials
Oxidative stress and impaired methylation are significant pathways that can help regulate hormones. A comprehensive nutrition assessment and targeted therapeutic interventions can help support these and other essential pathways. Both female and male hormone replacement. Very informative.
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